Rh incompatibility

Rh incompatibility is a condition that arises when a pregnant woman possesses Rh-negative blood while her developing baby carries Rh-positive blood. This mismatch in blood types can become more pronounced during situations such as medical termination of pregnancy (MTP) or other sensitizing events. Surprisingly, it takes only 0.01 ml to 0.03 ml of FMH for the isoimmunization of the mother (1), elevating the risk of Haemolytic Disease of the Newborn (HDN). To assess whether a Rh-negative mother has become sensitized, healthcare professionals (HCPs) conduct Indirect Coomb’s Test (ICT). This test not only aids in diagnosis but also serves as a therapeutic tool by enabling HCPs to educate Rh-negative women about their sensitization status.

In September 2020, we initiated a program offering free ICT testing to Rh-negative mothers based on a doctor’s recommendation. It raised awareness and the need for ICT testing, particularly in MTPs in Rh-negative mothers.

As yet another attempt to ā€˜bring life to lifeā€™, a dedicated microsite https://www.antid.com/ on Rh incompatibility has been created. This site would help the community of women in childbearing age group and healthcare professionals. Together, we can navigate the challenges of Rh incompatibility and help you make informed decisions for yourself and your loved ones.

Ref 1. Krywko DM, Yarrarapu SN, Shunkwiler SM. Kleihauer Betke Test. InStatPearls [Internet]Ā  Aug . StatPearls Publishing.